In the advancing Anthropocene, human-centred thinking and action are massively contributing to the destruction of our basis of life. It is crucial to see ourselves as part of our planet’s manifold interdependent living beings. The underscore between HUMAN and NATURE in the exhibition title represents interdependency and space, highlighting the complex relationship between humans and nature. Around 30 artists from the Künstlerhaus Vereinigung open up a broad narrative field with their transmedial works, negotiating the status quo of our threatened planet, exploring dystopian and visionary ideas for the future as well as gender-specific, ironic, and humorous approaches. The exhibition and its catalogue are intended to spark interest and action to further address this burning issue.